COURSE INTRODUCTION AND APPLICATION INFORMATION


Course Name
Introduction to Immunology
Code
Semester
Theory
(hour/week)
Application/Lab
(hour/week)
Local Credits
ECTS
MED 260
Fall/Spring
3
0
3
4
Prerequisites
None
Course Language
English
Course Type
Elective
Course Level
First Cycle
Mode of Delivery -
Teaching Methods and Techniques of the Course
Course Coordinator
Course Lecturer(s)
Assistant(s) -
Course Objectives This course aims to train the students with an introductory level in immunology.
Learning Outcomes The students who succeeded in this course;
  • 1-Define basic immunology concepts and terms.
  • 2-Describe the cells, tissues and organs related to immunology.
  • 3-Specify the stages of immune response and signs of inflammation.
  • 4-Explain natural and acquired immunity, related cells and antigen presentation.
  • 5-Classify the main disease groups associated with the dysregulation of the immune system.
  • 6-Explain examples of cancer-specific immune responses and their use in cancer treatment.
Course Description This course begins with a general introduction to how immune system cells and tissues work, followed by the development and migration of these cells under physiological conditions. The course will continue with the stages of immune response and inflammation under pathological conditions, and will focus on the basic mechanisms of immune responses.
Related Sustainable Development Goals

 



Course Category

Core Courses
Major Area Courses
Supportive Courses
X
Media and Managment Skills Courses
Transferable Skill Courses

 

WEEKLY SUBJECTS AND RELATED PREPARATION STUDIES

Week Subjects Required Materials
1 Introduction Examination of the posted syllabus, requirements and course flow
2 Immune system Cells and Tissues: Myeloid vs. Lymphoid Abul K Abbas, Andrew H Lichtman, Shiv Pillai, Cellular and Molecular Immunology 8th Edition Chapter 1 and 2 p 1-35
3 Development and Migration of Leukocytes Janeway C. and Medzhitov R. Immunobiology 8th Ed. Ch. 1
4 Phases of an Immune response and Inflammation Sherris Medical Microbiology Kenneth C. Ryan Chapter 2: Immune response to Infection. Innate (Natural) Immunity (Access Medicine- no page numbers)
5 Innate immune system: Mucosal Immunity and Microbiota “The human skin microbiome” Nature Reviews Microbiology 16, pages 143–155 (2018) doi:10.1038/nrmicro.2017.157 Abul K Abbas, Andrew H Lichtman, Shiv Pillai, Cellular and Molecular Immunology 8th Edition Chapter 14 p 289
6 Innate immune system: Phagocytosis and Complement system Jawetz Medical Microbiology Chapter 8: Immunity: Mechanisms of Innate Immunity: Innate (Natural) Immunity D. Complement System (Access Medicine- no page numbers)
7 Antigens and Antigen presentation Abul K Abbas, Andrew H Lichtman, Shiv Pillai, Cellular and Molecular Immunology 8th Edition Chapter 6 p 117-145
8 T lymphocytes and activation Abul K Abbas, Andrew H Lichtman, Shiv Pillai, Cellular and Molecular Immunology 8th Edition Chapter 8, 9, 10 and11 p 171-239
9 B lymphocytes and activation, antibody production and function Abul K Abbas, Andrew H Lichtman, Shiv Pillai, Cellular and Molecular Immunology 8th Edition Chapter 8, 12 and 13 p 239-289
10 Tolerance and Autoimmunity: Case study Abul K Abbas, Andrew H Lichtman, Shiv Pillai, Cellular and Molecular Immunology 8th Edition Chapter 15 p 325-351
11 Hypersensitivity and Allergy Abul K Abbas, Andrew H Lichtman, Shiv Pillai, Cellular and Molecular Immunology 8th Edition Chapter 19-20 p 417-437
12 Immunodeficiencies and Transplantation Immunology Abul K Abbas, Andrew H Lichtman, Shiv Pillai, Cellular and Molecular Immunology 8th Edition Chapter 17-21 p 373/459
13 Tumor Immunology Abul K Abbas, Andrew H Lichtman, Shiv Pillai, Cellular and Molecular Immunology 8th Edition Chapter 18 p 397-417
14 Immunotherapy of Cancer Lisa Butterfield, Howard Kaufmann, F. Marincola Cancer Immunotherapy Principles and Practice, Section II: Cancer Immunothrapy Targets and Classes 231-404
15 Poster presentations and Semester Review
16 Final Exam
Course Notes/Textbooks

Lisa Butterfield, Howard Kaufmann, F. Marincola Cancer Immunotherapy ISBN 9781620700976

Abul K Abbas, Andrew H Lichtman, Shiv Pillai, “Cellular and Molecular Immunology” 8th Edition ISBN 978-0 323-52324-0

Karren C Carroll, Jawetz, Melnick, & Adelberg’s Medical Microbiology, 27e 2018 ISBN 9780-0-71-82498-9

Kenneth J Ryan, Sherris Medical Microbiology 7th ed. 2018 ISBN 978-1-259-85980-9

Charles Janeway and Ruslan Medzhitov “Immunobiology” 9th Ed. ISBN 978-0815345848

Suggested Readings/Materials

Access Medicine online access to  Jawetz Medical Microbiology

Sherris Medical Microbiology will be provided by the Faculty of Medicine online acccess

Abul K Abbas, Andrew H Lichtman, Shiv Pillai, Cellular and Molecular Immunology 8th Edition is available through IEU library

Notes from Lisa Butterfield, Howard Kaufmann, F. Marincola Cancer Immunotherapy Principles and Practice will be provided during the course

 

EVALUATION SYSTEM

Semester Activities Number Weigthing
Participation
1
10
Laboratory / Application
Field Work
Quizzes / Studio Critiques
Portfolio
Homework / Assignments
1
10
Presentation / Jury
1
40
Project
Seminar / Workshop
Oral Exam
Midterm
Final Exam
1
40
Total

Weighting of Semester Activities on the Final Grade
3
60
Weighting of End-of-Semester Activities on the Final Grade
1
40
Total

ECTS / WORKLOAD TABLE

Semester Activities Number Duration (Hours) Workload
Course Hours
(Including exam week: 16 x total hours)
16
3
48
Laboratory / Application Hours
(Including exam week: 16 x total hours)
16
Study Hours Out of Class
15
1
15
Field Work
Quizzes / Studio Critiques
Portfolio
Homework / Assignments
1
10
Presentation / Jury
1
15
Project
Seminar / Workshop
Oral Exam
Midterms
Final Exams
1
32
    Total
120

 

COURSE LEARNING OUTCOMES AND PROGRAM QUALIFICATIONS RELATIONSHIP

#
Program Competencies/Outcomes
* Contribution Level
1
2
3
4
5
1

Explain the normal structure and functions of the human body at the molecular, cellular, tissue, organ and system levels, associate them with suggestions, practices and clinical situations (nutrition, exercise, vaccination, mental health, etc.); to protect and improve the health of individuals.

X
2

Describe the mechanisms of diseases at the molecular, cellular, tissue, organ and system levels and make evidence-based decisions by associating them with disease findings, diagnosis and treatment approaches.

X
3

Consider the ethical principles, scientific facts, legal regulations and the biopsychosocial and cultural characteristics of the patient in the medical decision making process. Place importance and respect the autonomy of patients and the confidentiality of patient information, within the framework of the law and the provisions of healthcare application standards.

X
4

Prioritize patient safety to minimize malpractice by carrying out risk assessment, take the necessary precautions, perform the necessary medical practice and record them.

5

Communicate healthily, openly and effectively with healthcare workers, patients and their relatives, with the communication structured on empathy and care, trust and constructiveness; while being respectful to language, belief, race and cultural characteristics.

6

By bearing in mind the patients’ values, beliefs, priorities, and needs; provide evidence-based options and include them in the decision making process.

7

Preserve our planet’s resources and consider its effects on the public and individual’s health, advocate to disseminate healthy lifestyle behaviors and modify factors that affect health adversely.

8

Reach current, valid and reliable information effectively using technology. Critically evaluate this information for solving problems in an evidence-based medical decision-making process, bearing in mind prevention, diagnosis, and management of diseases.

X
9

Identify problems, create hypotheses, conduct research and employ teamwork to analyze results for generation and dissemination of health-related scientific knowledge.

X
10

By taking feedback and evaluating their performance, determine the areas and options for improvement and implement them within a plan.

X
11

Care for their own personal health, safety and appearance, take the necessary precautions in order to set an example for their colleagues and society.

12

Continuously renew themselves in their medical knowledge by always bearing in mind their commitment to lifelong learning principles.

13

Using various communication tools, share their professionally gained knowledge in the field of healthcare, opinions, experiences, and evaluations with institutions, colleagues and the public.  Advocate for healthcare and contribute to developing policies to protect and improve it.

X

*1 Lowest, 2 Low, 3 Average, 4 High, 5 Highest